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Allergy & Sensitivity Summary

Allergy And Sensitivity Sensitivity To Benzene

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Based on your genetics, your genetic predisposition for Sensitivity To Benzene is

Normal
Low
Normal
High

What does this mean?

 Your genotype shows that you have no increased risk for benzene poisoning.

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How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Sensitivity To Benzene.

These are the genes tested for Sensitivity To Benzene:

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Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Sensitivity To Benzene?

Benzene is a colourless or light yellow-coloured liquid that can easily evaporate into the air at room temperature. It has a sweet odour and is highly flammable. Benzene is a natural component that is found in crude oil, gasoline, and cigarette smoke. Indoor air generally contains levels of benzene higher than those in outdoor air. The benzene in indoor air comes from products that contain benzene, such as glues, paints, furniture wax, and detergents. Benzene itself is non-toxic, but when the level of benzene in the air exceeds the standards, it poses harmful risks to human health and the environment. Sensitivity to benzene occurs when an individual is more prone to developing symptoms of benzene toxicity upon exposure to the compound. Children and pregnant women are more likely to have sensitivity to benzene as compared to healthy adults.

How It Affects Your Body

After inhalation of benzene, it will be absorbed and distributed throughout the body. It accumulates in the body's bone marrow and fat temporarily. The liver and bone marrow will then work together to break down benzene compounds, which can later be exhaled out.

However, individuals with sensitivity to benzene are unable to do so, thus leading to toxic levels of benzene accumulation in the body. Benzene metabolites accumulate in the liver during detoxification. This results in harmful effects on the bone marrow which may cause anaemia, especially after a long-term exposure (a year or more) to benzene. It can also cause excessive bleeding and can affect the immune system, increasing the chances of infection. In addition, it may also lead to nerve damage.

Signs and Symptoms - Immediate

Signs and Symptoms - Long Exposure

Suggested Lifestyle Changes

Lifestyle Recommendations:

  1. You are advised to reduce exposure to benzene products, as long term exposure to benzene can have harmful effects on the bone marrow and may cause anaemia.
  2. Avoid smoking or visiting smoking areas, such as pubs, bars and clubs. Cigarette smoke is said to be the largest contributor of benzene to indoor air.
  3. Personal protective equipment is highly encouraged for industrial workers to minimise occupational exposure to benzene.
  4. Immediately seek for medical attention when exposed to high levels of benzene in the air or when suspected signs and symptoms of benzene toxicity are observed.

Result Explanation Recommendations:

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