Nutrition & Diet

Iron Requirement

All of your cells contain some iron, but most of the iron in your body is in your red blood cells.

Your Result

Based on your genetics, your genetic predisposition for Iron Requirement is

High

What does it mean?

Likely to have low iron & haemoglobin levels. Your genotypes are associated with low iron and haemoglobin levels and you are likely to have an increased risk for iron deficiency. Review your iron intake.

Suggested Lifestyle Changes

Dietary Recommendations

1

Iron comes in two forms - heme iron from animal sources, and non-heme iron from plants. Heme iron is absorbed more readily than non-heme iron.

2

Foods high in iron include beef, poultry, oysters, fish and organ meats such as liver. Good sources of non-heme iron include beans, fortified cereals, spinach and other dark leafy greens.

3

Vitamin C enhances absorption of non-heme iron, while wholegrains, legumes and nuts inhibit absorption by around 50% due to their phytate content. Polyphenols in coffee and tea may also reduce absorption. Calcium reduces absorption of both heme and non-heme iron.

4

Optimise iron bioavailability from your diet by avoiding tea or coffee, and eating calcium rich foods together with iron rich meals. Eating fruits and vegetables together with an iron rich meal will improve its absorption, as they contain vitamin C and organic acids.

Supplement Recommendations

1

The most common form of supplemental iron is ferrous iron and ferric iron. Opt for the ferrous form as it is more bioavailable.

2

Taking vitamin C with iron enhances iron absorption. High doses of supplemental iron (45 mg per day or more) may cause gastrointestinal side effects, such as nausea and constipation. If prone to gastric irritation, look for other forms of iron, such as heme iron polypeptides, carbonyl iron, iron amino-acid chelates, and polysaccharide-iron complexes, as these may have fewer gastrointestinal side effects.

3

As calcium can interfere with iron absorption, avoid taking these supplements together.

4

Excess iron may be harmful to your body. It is advised that you confirm deficiency through a blood test, and discuss the need for supplementation with your health practitioner.

What Is Iron Requirement
and How Can It Affect You

What is Iron Requirement

Iron is an essential mineral, and a key component of hundreds of proteins, including oxygen-carrying hemoglobin in red blood cells, and myoglobin (found in muscle cells). Absorption, transport and storage of iron are tightly regulated as it is both essential, and potentially toxic.

Iron deficiency is the most common nutrient deficiency in the world, leading to symptoms such as anemia, fatigue and palpitations. If you suffer from chronic infections, and often feel sluggish, weak, and unable to focus, insufficient iron levels may be a factor. Individuals following a vegetarian or vegan diet, and atheletes typically have higher iron requirements.

Genetic variations in the transferrin, transferrin receptor, transmembrane protease (TMPRSS6) genes are associated with lower iron status.

RDA is 8mg for men. Women have a higher requirement, at 18mg for 19- 50 years old, and 8mg for women 51 years and over.

Do You Have Iron Deficiency?

Do you have any of the following signs and symptoms? See your doctor if you begin experiencing any of the following symptoms:

Factors Affecting Iron Deficiency

You may be at risk of Iron deficiency if you are:

Food Sources Containing Iron

Iron

Understanding Your Results

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

High

Genes tested

This result is based on the SNPs (single nucleotide polymorphism) that are associated with Iron Requirement.

GenesYour GenotypeWhat It Means
TMPRSS6_exon17TTLower serum iron and hemoglobin levels
TMPRSS6_exon13GGLower iron and hemoglobin levels

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.

This result is limited to existing scientific research.

Consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

If you think you have the symptoms, consult with a healthcare professional.