Health Risks

Non-Alcoholic Fatty Liver Disease

NAFLD refers to the accumulation of excessive fats in liver cells, a condition known as steatosis and it is not due to excess alcohol consumption.

DEMO Result

Based on your genetics, your personal predicted risk is

37.09


Your risk for Non-Alcoholic Fatty Liver Disease also depends on other factors, including lifestyle and genetic variants not covered by this test.

The population risk for Non-Alcoholic Fatty Liver Disease is 30.0

How To Use This Test


This test SHOULD NOT be used to diagnose Non-Alcoholic Fatty Liver Disease or any other health conditions.


Please talk to a healthcare professional if you have a family history, if you think you might have this condition or if you have any concerns about your results.

Intended Uses

This predicted personal genetic risk merely considers the genetic/genotype effect towards the disease in an individual without taking into account the environmental factors such as lifestyles, diet and their environment

This result is based on the SNPs (single nucleotide polymorphism) that are associated with Non-Alcoholic Fatty Liver Disease.

Read more


Limitations

The results of this test do not diagnose Non-Alcoholic Fatty Liver Disease or related conditions. This should not be used as a diagnostic tool.

This result does not include all possible variants or genes associated with Non-Alcoholic Fatty Liver Disease.

This result is limited to existing scientific research.

Lifestyle & Other Risk Factors Can Influence The Risk of Developing Non-alcoholic fatty liver disease

Genetics are NOT the only risk factor for Non-Alcoholic Fatty Liver Disease.

Non-Alcoholic Fatty Liver Disease is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.

The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Non-Alcoholic Fatty Liver Disease.

Blood pressure
Cholesterol Level

Having high triglyceride levels in the blood increases the risk of developing NAFLD.

Blood pressure
Blood Pressure

Having high blood pressure increases the risk of developing NAFLD.

Weight
Abdominal Fat

People who have increased abdominal fat or higher waist circumference are at higher risk of developing NAFLD.

Age
Age

People in their 40s and 50s who are at high risk of heart disease, are at higher risk of developing NAFLD.

Suggested Lifestyle Changes

Exercise Recommendations

1

Keep a healthy lifestyle by doing regular exercises. Some examples are: 150 minutes of moderate intensity exercise (brisk walking, easy jogging, gardening ) per week, 75 minutes of vigorous intensity exercise (running, swimming, cycling) per week, or muscle strengthening (lifting weights, working with resistance bands) exercises twice per week.

Dietary Recommendations

1

Avoid heavy alcohol consumption as it can cause damage to the liver.

2

Have a balanced diet with low levels of saturated and trans fats (baked goods, sugary food, margarine, processed food) and simple sugars. Having a healthy weight can help reduce your risk of developing NAFLD.

3

Avoid food with high saturated and trans fat content, so that you can maintain a healthy levels of triglyceride in your blood.

What Is Non-Alcoholic Fatty Liver Disease
and How Can It Affect You

What is Non-Alcoholic Fatty Liver Disease

Non‐alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. NAFLD refers to the accumulation of excessive fats in liver cells, a condition known as steatosis and it is not due to excess alcohol consumption.

The prevalence of NAFLD is up to 30% in developed countries and nearly 10% in developing nations, making NAFLD the most common liver condition in the world.

NAFLD is strongly associated a with a number of metabolic risk factors including increased abdominal fat, poor ability of the body to use the hormone insulin or a condition better known as insulin resistance, high blood pressure and high blood levels of triglycerides, a type of fat and most significantly, obesity.

Over time, some people in these conditions (obesity, metabolic syndrome) can develop inflammation (swelling) of the liver. In some people, this inflammation can cause injury to the liver cell resulting in scarring of the liver tissue. Over years as more and more scar tissue begins building up, the liver will begin to harden a condition known as cirrhosis. This is considered a severe stage of the disease and it will only progress further causing liver failure or it increases the risk of developing liver cancer (Hepatocellular Carcinoma).

Symptoms Of Nafld

NAFLD
The disease hardly causes any signs or symptoms. Some patients may experience discomfort in the right upper side of the abdomen or fatigue.

NASH or Cirrhosis
In patients where the disease has progressed into a much severe stage they may experience yellowing of the skin and eyes a condition known as jaundice.

Children may also report non-specific symptoms, including abdominal pain, fatigue, irritability, headaches and difficulty concentrating.

How Can Non Alcoholic Fatty Liver Disease Affect You?

NAFLD causes central obesity (abdominal fat) or diabetes. NAFLD patients are at increased risk of liver-related as well as heart -related mortality, and NAFLD is rapidly becoming the leading indication for liver transplantation.

NAFLD is a silent disease as it hardly shows any symptoms at an early stage. However when you start to experience pain on the right upper side of the abdomen and yellowing of the skin and eyes due to increase level of liver enzymes in the blood, the disease unfortunately has progressed into a much severe stage.

If you have a family history of this condition or think you have the symptoms, consult with a healthcare professional.

Understanding Your Results

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

37.09

Genes tested

This result is calculated based on the following SNPs (single nucleotide polymorphism) that are associated with Non-Alcoholic Fatty Liver Disease.

GenesYour GenotypeWhat It Means
SOD2TTIncreased risk
KLF6GGIncreased risk

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.

This result is limited to existing scientific research.

Consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.