Nutrigenomics Iron Requirement

Based on your genetics, your genetic predisposition for Iron Requirement is

High
Low
Normal
High

What does this mean?

Likely to have low iron & haemoglobin levels Your genotypes are associated with low iron and haemoglobin levels and you are likely to have an increased risk for iron deficiency. Review your iron intake.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Iron Requirement.

Genes
Your Genotype
What it means?
Genes: TMPRSS6_exon17
Your Genotype: TT
What it means? Lower serum iron and haemoglobin levels
Genes: TMPRSS6_exon13
Your Genotype: GG
What it means? Lower iron and haemoglobin levels
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Iron Requirement?

Iron is an essential mineral, and a key component of hundreds of proteins, including oxygen-carrying hemoglobin in red blood cells, and myoglobin (found in muscle cells). Absorption, transport and storage of iron are tightly regulated as it is both essential, and potentially toxic.

Iron deficiency is the most common nutrient deficiency in the world, leading to symptoms such as anemia, fatigue and palpitations. If you suffer from chronic infections, and often feel sluggish, weak, and unable to focus, insufficient iron levels may be a factor. Individuals following a vegetarian or vegan diet, and atheletes typically have higher iron requirements.

Genetic variations in the transferrin, transferrin receptor, transmembrane protease (TMPRSS6) genes are associated with lower iron status.

RDA is 8mg for men. Women have a higher requirement, at 18mg for 19- 50 years old, and 8mg for women 51 years and over.

Do you have Iron deficiency?

Factors affecting Iron deficiency

You may be at risk of Iron deficiency if you are:

1
2
3
4
5
6
7

Food Sources Containing Iron

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Iron comes in two forms - heme iron from animal sources, and non- heme iron from plants. Heme iron is absorbed more readily than non- heme iron.
  2. Foods high in iron include beef, poultry, oysters, fish and organ meats such as liver. Good sources of non-heme iron include beans, fortified cereals, spinach and other dark leafy greens.
  3. Vitamin C enhances absorption of non-heme iron, while wholegrains, legumes and nuts inhibit absorption by around 50% due to their phytate content. Polyphenols in coffee and tea may also reduce absorption. Calcium reduces absorption of both heme and non-heme iron.
  4. Optimise iron bioavailability from your diet by avoiding tea or coffee, and eating calcium rich foods together with iron rich meals. Eating fruits and vegetables together with an iron rich meal will improve its absorption, as they contain vitamin C and organic acids.

Supplement Recommendations:

  1. Based on your genetic profile, you do not need supplementation. Consider testing your iron levels if you follow a vegetarian or vegan diet, or often fall ill, feel weak or lethargic.
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If you think you have the symptoms, consult with a healthcare professional.