Health Risks

Osteoarthritis

Osteoarthritis is a common disease of the joints that primarily occurs in older adults, mainly caused by the body's failed attempts to repair damages to the cartilage.

DEMO Result

Based on your genetics, your personal predicted risk is

22.64


Your risk for Osteoarthritis also depends on other factors, including lifestyle and genetic variants not covered by this test.

The population risk for Osteoarthritis is 20.0

How To Use This Test


This test SHOULD NOT be used to diagnose Osteoarthritis or any other health conditions.


Please talk to a healthcare professional if you have a family history, if you think you might have this condition or if you have any concerns about your results.

Intended Uses

This predicted personal genetic risk merely considers the genetic/genotype effect towards the disease in an individual without taking into account the environmental factors such as lifestyles, diet and their environment

This result is based on the SNPs (single nucleotide polymorphism) that are associated with Osteoarthritis.

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Limitations

The results of this test do not diagnose Osteoarthritis or related conditions. This should not be used as a diagnostic tool.

This result does not include all possible variants or genes associated with Osteoarthritis.

This result is limited to existing scientific research.

Lifestyle & Other Risk Factors Can Influence The Risk of Developing Osteoarthritis

Genetics are NOT the only risk factor for Osteoarthritis.

Osteoarthritis is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.

The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Osteoarthritis.

Exercise
Injury

Significant injury, such as ligament damage, can eventually lead to osteoarthritis.

Gender
Gender

Women are more likely to develop osteoarthritis, compared to men.

Weight
Weight

Excessive weight can put stress on joints and promote cartilage damage.

Age
Age

Osteoarthritis is more common among the elderly, but even young adults can develop osteoarthritis.

Suggested Lifestyle Changes

Exercise Recommendations

1

Strengthening the muscles with weight training will support and protect your joints. If your joints are painful or swollen it is recommended you to take a rest day or two in between workout.

2

Low-impact aerobic exercises are lighter and easier on your joints which includes walking, bicycling , swimming. Try not to strain your joints.

Lifestyle Recommendations

1

Maintain a healthy weight. Being overweight and obese increases the risk of developing osteoarthritis as the excess weight puts too much pressure on the joints and cartilages.

Dietary Recommendations

1

Consume enough magnesium as it helps maintain and improve joint and cartilage health.

2

Some antioxidants, found in fruits and veggies like apples, onions, shallots, and strawberries, may also help reduce joint inflammation and pain.

3

Cartilage is made of collagen, and your body requires vitamin C to make this protein. To build cartilage in your knees, make sure you are getting the recommended daily amount of this antioxidant vitamin -- 75 milligrams for women and 90 milligrams for men.

What Is Osteoarthritis
and How Can It Affect You

What is Osteoarthritis

Osteoarthritis is the most common type of arthritis (informally known as joint disease), which occurs when the cartilage (a cushioning surface or rubber like padding) that protects the ends of the bones at the joints, wears down over the time. This will cause the bone to rub against another bone, leading to pain, swelling and stiffness to the joint.

In healthy cartilage, there is a balance between buildup and breakdown of the tissue. This balance is lost in osteoarthritis, leading to cartilage damage and, over time, complete breakdown. Without the protection of the cartilage, bone damage occurs at the joint. In response, the body builds new bone, which leads to overgrowth and reduced mobility of the joints. In addition, the cartilage damage triggers an immune response, causing inflammation of other joint tissues and leading to further joint damage.

Symptoms Of Osteoarthritis

Symptoms of osteoarthritis includes:

How Does Osteoarthritis Affect You?

Osteoarthritis can occur in any joint, but it often affected joints in the hands, knees, hips, and spine. In the long run the joints can become weak and the pain may become worse. This disorder is often asymmetric where a patient may have severe, debilitating osteoarthritis of one knee with almost normal function of the opposite leg.

A day to day activity becomes challenging to perform due to the pain and stiffness caused by OA.

If you have a family history of this condition or think you have the symptoms, consult with a healthcare professional.

Understanding Your Results

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

22.64

Genes tested

This result is calculated based on the following SNPs (single nucleotide polymorphism) that are associated with Osteoarthritis.

GenesYour GenotypeWhat It Means
IL1BCTIncreased risk of osteoarthritis
COL6A4P1AGIncreased risk of osteoarthritis

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.

This result is limited to existing scientific research.

Consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.