Health Risks

Osteoporosis

Osteoporosis causes the bones to become weak and brittle.

DEMO Result

Based on your genetics, your personal predicted risk is

7.4


Your risk for Osteoporosis also depends on other factors, including lifestyle and genetic variants not covered by this test.

The population risk for Osteoporosis is 10.6

How To Use This Test


This test SHOULD NOT be used to diagnose Osteoporosis or any other health conditions.


Please talk to a healthcare professional if you have a family history, if you think you might have this condition or if you have any concerns about your results.

Intended Uses

This predicted personal genetic risk merely considers the genetic/genotype effect towards the disease in an individual without taking into account the environmental factors such as lifestyles, diet and their environment

This result is based on the SNPs (single nucleotide polymorphism) that are associated with Osteoporosis.

Read more


Limitations

The results of this test do not diagnose Osteoporosis or related conditions. This should not be used as a diagnostic tool.

This result does not include all possible variants or genes associated with Osteoporosis.

This result is limited to existing scientific research.

Lifestyle & Other Risk Factors Can Influence The Risk of Developing Osteoporosis

Genetics are NOT the only risk factor for Osteoporosis.

Osteoporosis is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.

The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Osteoporosis.

Lifestyle
Bone Structure and Body Weight

Petite and thin women have a greater chance of developing osteoporosis. One reason is that they have less bone to lose than women with more body weight and larger frames. Similarly, small-boned, thin men are at greater risk than men with larger frames and more body weight.

Family
Family History

If your parents or grandparents have had any signs of osteoporosis, such as a fractured hip after a minor fall, there is an increased likelihood for developing osteoporosis.

Gender
Gender

Women over the age of 50 are the most likely people to develop osteoporosis. The condition is 4 times as likely in women than men. Women's lighter, thinner bones and longer life spans are part of the reason they have a higher risk.

Age
Age

Your bone density peaks around age 30. After that, you’ll begin to lose bone mass.

Suggested Lifestyle Changes

Supplement Recommendations

1

If you are unable to get sufficient calcium from your diet (lactose intolerant), you can opt for supplementation of magnesium and vitamin D to prevent bone resorption and osteoporosis. Adults between the ages 18 and 50 require 1,000 milligrams of calcium a day. Women who are 50 and above and men who turn 70 the daily intake of calcium increases to 1,200 milligrams a day. The daily total (diet and supplement combined) calcium intake should not exceed 2,000 milligrams per day for people older than 50.

Lifestyle Recommendations

1

Stop smoking and reduce your alcohol intake, as it may prevent lowering of your bone mineral density (BMD).

2

Adapt physical activity such as aerobic exercises, coordination and balance exercises to improve bone formation, to preserve bone mass and to prevent bone loss

Dietary Recommendations

1

Have a balanced diet with plenty of fruits and vegetables, adequate dairy (calcium) and protein.

2

Limiting intake of food with low nutrient content such as soft drinks and fast food.

3

Make sure you have sufficient intake of calcium. Good sources of calcium includes low-fat dairy products, dark green leafy vegetables, canned salmon or sardines with bones, soy products (tofu), calcium-fortified cereals and orange juice.

What Is Osteoporosis
and How Can It Affect You

What is Osteoporosis

Osteoporosis is a bone disease that occurs when the body loses too much bone, makes too little bone, or both. As a result, bones become weak and may break from a fall or, in serious cases, from sneezing or minor bumps.

Osteoporosis is the most common bone disease in humans. It is a silent disease that affects an enormous number of people, of both sexes and all races, and it is more common in the ageing population. Osteoporosis is more commonly in Caucasians, women, and older people.

Symptoms Of Osteoporosis

Symptoms to watch includes:

How Does Osteoporosis Affect You?

Bone tissue is continuously being resorbed and rebuilt; bone loss occurs if the resorption rate exceeds the formation rate. Bone resorption is a process of transferring calcium in the bone tissue to the blood by the breakdown bone tissue. With menopause and advancing age, an imbalance happen between resorption and formation rates of bone tissue where resorption becomes higher than absorption, thereby increasing the risk of fracture. Fractures

occurring spontaneously or following minor trauma such as fall from a standing height or less are very common in osteoporotic individuals.

If you have a family history of this condition or think you have the symptoms, consult with a healthcare professional.

Understanding Your Results

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

7.4

Genes tested

This result is calculated based on the following SNPs (single nucleotide polymorphism) that are associated with Osteoporosis.

GenesYour GenotypeWhat It Means
ESR1TTTypical
ALDH7A1AATypical
VDR_intron8GGReduced risk of osteoporosis
LRP5GGTypical

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.

This result is limited to existing scientific research.

Consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.