Health Risks

Stroke

Stroke occurs when the blood flow in the brain is interrupted or reduced, preventing brain tissues from getting enough oxygen and nutrients.

DEMO Result

Based on your genetics, your personal predicted risk is

1.34


Your risk for Stroke also depends on other factors, including lifestyle and genetic variants not covered by this test.

The population risk for Stroke is 0.7

How To Use This Test


This test SHOULD NOT be used to diagnose Stroke or any other health conditions.


Please talk to a healthcare professional if you have a family history, if you think you might have this condition or if you have any concerns about your results.

Intended Uses

This predicted personal genetic risk merely considers the genetic/genotype effect towards the disease in an individual without taking into account the environmental factors such as lifestyles, diet and their environment

This result is based on the SNPs (single nucleotide polymorphism) that are associated with Stroke.

Read more


Limitations

The results of this test do not diagnose Stroke or related conditions. This should not be used as a diagnostic tool.

This result does not include all possible variants or genes associated with Stroke.

This result is limited to existing scientific research.

Lifestyle & Other Risk Factors Can Influence The Risk of Developing Stroke

Genetics are NOT the only risk factor for Stroke.

Stroke is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.

The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Stroke.

Age
Age

The likelihood of having a stroke increases with age for both males and females, and is more common in people above age 65.

Gender
Gender

Women have more strokes than men and stroke kills more women than men. Women tend to live longer than men and are older when they have a stroke.

Family
Family History

Having family members who had a stroke, especially before the age of 65, increases the risk of developing stroke.

Blood pressure
Blood Pressure

High blood pressure, or hypertension, is a leading cause of stroke and the most significant controllable risk factor.

Smoking
Smoking

The nicotine and carbon monoxide in cigarette smoke damage the cardiovascular system and pave the way for a stroke.

Diabetes
Diabetes

Diabetes mellitus is an independent risk factor for stroke. Many people with diabetes also have high blood pressure, high blood cholesterol and are overweight — increasing their risk even more.

Diet
Diet

Diets high in saturated fat, trans fat and cholesterol can raise blood cholesterol levels. Diets high in sodium (salt) can increase blood pressure. Diets with high calories can lead to obesity.

Weight
Weight

Excess body weight and obesity are linked with an increased risk of high blood pressure, diabetes, heart disease and stroke. Losing as little as 2 to 5 kg can make a significant difference in your risks.

Suggested Lifestyle Changes

Lifestyle Recommendations

1

Maintain a healthy body weight and do more physical activities to reduce stroke risk. It is recommended do at least 150 minutes of activities like brisk walking or cycling every week.

2

Quit smoking as studies have shown that stroke risk decreased significantly after stopping of cigarette smoking.

3

Reduce alcohol consumption, as too much alcohol can cause high blood pressure and irregular heartbeat which increases the risk of having stroke.

Dietary Recommendations

1

Limiting the intake of saturated fats, salt (sodium) and alcohol while increasing the intake of fruits, vegetables, and potassium can help to reduce stroke risk.

2

Modest consumption of fish (for example 1-2 servings/week) which contains omega-3 fatty acids may reduce the risk of stroke.

3

Increase lycopene intake. Low levels of lycopene is associated with an increased risk of stroke. Lycopene can be found in red and pink plant and vegetables, for example: tomatoes, red carrots , watermelon, pink grapefruits.

4

Reduce the intake of refined carbohydrates (processed foods: cakes, pasta,cookies, donuts), sugar and refined starches. Instead, take cereal fiber as it may help reduce stroke.

5

Having a mediterranean diet can significantly decrease stroke risk. Mediterranean diet is rich in green leafy vegetables, fruits, nuts everyday, olive oil, and fish.

What Is Stroke
and How Can It Affect You

What is Stroke

Stroke occurs when the blood flow in the brain is interrupted or reduced, preventing brain tissues from getting enough oxygen and nutrients. Within minutes, brain cells begin to die, which could affect memory and muscle control.

The blood flow to the brain can be interrupted due to blood clot formation in the blood vessel or a blood vessel that ruptures and stops the blood flow to the brain.

Stroke is also a leading cause of functional impairments, with 20% of survivors requiring institutional care after 3 months and 15% to 30% being permanently disabled.

How Does Stroke Affects You?

The degree of which stroke affects a person depends on the location of the blood flow obstruction and the amount of brain tissue affected. Since one side of the brain controls the other side of the body, a stroke affecting one side of the brain will result in complications to the opposite side of the body.

If stroke happens in the left brain:
The right side of the body will be affected, therefore causing some or all of the effect as below
Paralysis occurs on the right side of the body
Speech/language disruption
Memory loss

If stroke happens in the right brain:
Left side of the body will be affected, causing some or all of the following
Paralysis happens on the left side of the body
Problem with vision
Memory loss

Symptoms Of Stroke

Symptoms of stroke includes:

If you have a family history of this condition or think you have the symptoms, consult with a healthcare professional.

Understanding Your Results

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

1.34

Genes tested

This result is calculated based on the following SNPs (single nucleotide polymorphism) that are associated with Stroke.

GenesYour GenotypeWhat It Means
ESR1TTTypical
CDKN2A/CDKN2BGGIncreased risk of stroke
NINJ2_intron1AGIncreased risk of stroke
NINJ2_intron2AAIncreased risk of stroke
PON1AGIncreased risk of stroke
PRKCHAGIncreased risk of stroke
PDE4D_intron1ATTypical
PDE4D_intron2TTLowered risk of stroke
APLNRGGIncreased risk of stroke

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.

This result is limited to existing scientific research.

Consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.