Carrier X-linked Severe Combined Immunodeficiency

Based on your genetics, your genetic predisposition for X-linked Severe Combined Immunodeficiency is

Negative
Negative
Positive

What does this mean?

 Your genotype indicates that you do not carry the genetic mutation of X-linked severe combined immunodeficiency.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with X-linked Severe Combined Immunodeficiency.

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Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is X-linked Severe Combined Immunodeficiency?

X-linked severe combined immunodeficiency (SCID) is an inherited disorder of the immune system that occurs almost exclusively in males. Boys with X-linked SCID are prone to recurrent and persistent infections because they lack the necessary immune cells to fight off certain bacteria, viruses, and fungi. Many infants with X-linked SCID develop chronic diarrhoea, a fungal infection called thrush, and skin rashes.

Signs and Symptoms

Possible Inheritance Modes for X-linked Severe Combined Immunodeficiency

There is one inheritance mode of X-linked Severe Combined Immunodeficiency. Inheritance mode is how a gene will be passed down from parent to offspring.

X Recessive

X-linked recessive disorders are also caused by mutations in genes on the X chromosome. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation would have to occur in both copies of the gene to cause the disorder. Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females.

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