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Allergy And Sensitivity Summary
Alcohol Flush
Allergy To Cats
Allergy To Dust Mites
Allergy To Egg
Allergy To Peanuts
Caffeine Metabolism
Gluten Sensitivity
Hay Fever
Histamines Intolerance
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Allergy And Sensitivity Alcohol Flush

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Based on your genetics, your genetic predisposition for Alcohol Flush is

Normal
Low
Normal
High

What does this mean?

Likely to have typical alcohol metabolism Your genotype indicates that you are unlikely to develop alcohol flush upon alcohol consumption. Nevertheless, if you were to drink, drink moderately and avoid binge drinking.

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How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Alcohol Flush.

Genes
Your Genotype
What it means?
Genes: ALDH2
Your Genotype: GG
What it means? Typical alcohol metabolism
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Alcohol Flush?

When alcohol is consumed, alcohol is absorbed into blood from stomach and intestines. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are the enzymes that helps in the the conversion of alcohol to acetaldehyde, as well as the breakdown of alcohol molecule, so that it can be eliminated from the body. More than 90% of body alcohol is oxidized to acetic acid, while the remaining one is excreted in the sweat, urine or given off through breath.

How It Affects Your Body

When you drink alcohol, your liver will first break alcohol down into acetaldehyde (toxic substance). Then, ALDH2 (enzyme aldehyde dehydrogenase 2) will convert the toxic substance into a non-toxic substance known as acetic acid.

Individuals who are prone to alcohol flush have the issue of their body not being able to produce the ALDH2 enzyme, thus causing acetaldehyde to build up in their blood. The cause for this is a genetic variant in the ALDH2 gene. This variation affects the gene function, therefore the body is unable to produce enough of the enzyme to breakdown the toxic acetaldehyde compound.

The accumulation of the toxic substance would stimulate a series of physiological reactions. Eventually, the body experiences an increase in temperature, elevated blood pressure, rapid heart rate and flushing reaction.

Signs and Symptoms

Suggested Lifestyle Changes

Lifestyle Recommendations:

  1. Control your alcohol consumption. Based on the NHS guideline, women should not be drinking more than 2.5 UK units (equivalent to 25ml) of pure alcohol per day, while men should be limited to 3.75 UK units (equivalent to 37.5ml) of pure alcohol per day. However, units of alcohol can vary among different alcohols and one drink can contain up to several units.
  2. Do not drink on an empty stomach. Either choose to eat before consuming alcohol or have your meal while you drink. Studies have shown that eating before consuming alcohol helps to slow down your body? absorption of the alcohol and also protects the lining of the stomach.
  3. To prevent a hangover, rehydrate your body before going to bed.
  4. To reduce the risk of hangovers, know your limitations and stop drinking when signs of alcohol flush begin to appear.

Exercise Recommendations:

  1. Exercising the day after drinking can reduce performance and get tired easily. The reason being is that your liver is working to clear out alcohol toxins before eliminating lactic acid produced after exercise will be delayed. Hence, the accumulated lactic acid in the body will lead to muscle soreness and cramps.
  2. Alcohol drinks can increase urine production, where the water loss can also result in dehydration. Exercising can also further dehydrate the body as your body produces sweat, which reduces your exercise performance. It is important to drink more water to help your body to stay hydrated throughout your workout.
  3. In general, it is advised not to consume alcohol because of its health risk and how it will reduce your exercise performance in the long run.

Result Explanation Recommendations:

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