Skin Skin Glycation

Based on your genetics, your genetic predisposition for Skin Glycation is

High
Low
Normal
High

What does this mean?

Likely to have high risk of skin glycation. Likely to have high risk of skin glycation.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Skin Glycation.

Genes
Your Genotype
What it means?
Genes: AGER
Your Genotype: CC
What it means? Typical
Genes: AGER, PBX2
Your Genotype: TT
What it means? Typical
Genes: GLO1
Your Genotype: TT
What it means? Increased risk of skin glycation by accumulation of skin advanced glycation end-product (AGE)
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Skin Glycation?

If glucose is not metabolised properly, collagen and elastin fibres in the skin can bind to excess sugar molecules. This results in the production of advanced glycation end products (AGEs), which results in skin inflammation, poor skin healing, loss of skin elasticity, and accelerated skin aging. Glycation has been described as caramelization (hardening) of the skin from the inside out. The skin-damaging effects of glycation causes wrinkles, dryness, skin laxity. Young skin has a network of supportive collagen fibres that lose their elasticity with age and as a result of glycation. Some genetic variations are responsible for maintaining serum glucose levels, energy intake, and energy release, also controls glycation of the skin. Having variations in such genes can alter your body's ability to maintain normal glucose levels and interfere with energy metabolism, both of which lead to skin glycation.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Avoid grilling, frying, deep-fat frying or roasting your food as it may produce high level of AGEs.
  2. Avoid consuming food with high sugar content such as carbonated drinks and sweets as it may increase the glycation stress.
  3. Consume moderate or minimal alcohol intake as alcohol metabolites can increase glycation stress.
  4. Cinnamon, cloves and oregano can help to protect against fructose-induced AGE formation.

Supplement Recommendations:

  1. Mixture of herbal extracts from chamomile, hawthorn berry and grape leaf has been found to prevent the formation of AGEs.
  2. Studies show that consumption of probiotic supplementation may decrease blood sugar level, oxidative stress and early glycation.
  3. Carnosine is known as AGE inhibitor, it can be used as oral supplement or applied via skincare products.

Lifestyle Recommendations:

  1. Maintain reasonable skeletal muscle mass such as performing muscle load training and moderate exercise as blood glucose is mostly consumed in skeletal muscle.
  2. Eat slowly, chew food well and consume foods with low glycemic index as this eating habit can reduce glycation stress.

Result Explanation Recommendations:

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    If you think you have the symptoms, consult with a healthcare professional.