Health Risks Perennial Allergic Rhinitis

Based on your genetics, your genetic predisposition for Perennial Allergic Rhinitis is

Normal
1.08
0
23.78
100%

What does this mean?

 Your genotypes indicate that you have a typical risk for perennial allergic rhinitis (AR).

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

1.08

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Perennial Allergic Rhinitis.

Genes
Your Genotype
What it means?
Genes: MS4A2_3'-UTR
Your Genotype: GG
What it means? Reduced risk
Genes: MS4A2_exon7
Your Genotype: AA
What it means? Typical
Genes: EPS15
Your Genotype: CC
What it means? Typical
Genes: IL4
Your Genotype: TT
What it means? Typical
Genes: TNF-A
Your Genotype: TT
What it means? Typical
Genes: FOXP3
Your Genotype: AC
What it means? More susceptible to AR
Genes: TSLP
Your Genotype: CT
What it means? Increased risk
Genes: IL13
Your Genotype: GG
What it means? Typical
Genes: C11ORF30
Your Genotype: GG
What it means? Typical
Genes: HLA-DQB1
Your Genotype: TT
What it means? Typical
Genes: ADAM33
Your Genotype: CC
What it means? Reduced risk
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Perennial Allergic Rhinitis?

Perennial rhinitis can be defined clinically as an inflammatory condition of the nose characterised by nasal obstruction, sneezing, itching, or rhinorrhoea, occurring for an hour or more on most days throughout the year. This allergic reaction is triggered when the nose and/or eyes comes into contact with allergens found in the environment such as pollens, dust mite, moulds and animal hair.
When the immune system recognizes a harmless substance as if it is harmful, it triggers an allergic reaction (like launching an “attack”). When people are exposed to an allergen that they are sensitive towards, their nasal passages become inflamed, causing sneezing, irritation, airflow obstruction, and mostly clear nasal discharge is produced.

How It Affects Your Body

Perennial allergic rhinitis affects the body's immune system by causing it to perceive harmless substances like pollen, dust mites, and animal fur as harmful invaders.Immune cells in the body initiate an immune response as a defense mechanism.

The inhaled allergens bind to a protein called Ig-E on the surface of these immune cells, triggering the release of histamine. Histamine stimulates mucus production, nasal itching and sneezing symptoms.

Allergic rhinitis may also cause poor sleep quality and memory, fatigueness, and depression. In severe cases, these symptoms may cause a major disturbance to a person’s day-to-day activities and contribute to an overall reduced quality of life.

General Signs and Symptoms

Severe Signs and Symptoms

Risk Factors Can Influence The Risk of Developing Perennial allergic rhinitis

Genetics are NOT the only risk factor for Perennial Allergic Rhinitis.
Perennial Allergic Rhinitis is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Perennial Allergic Rhinitis.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. An antioxidant-rich diet (especially vitamin C) has been shown to reduce AR symptoms. Having this diet during childhood may contribute to prevention of AR. Examples of antioxidant-rich foods include citrus fruits (e.g. oranges, kiwi, grapefruit, lemons), grapes, blueberries, strawberries, beetroot, spinach, and beans.
  2. Consume more fruits and vegetables daily as they have natural anti-inflammatory benefits. Studies found that individuals who ate lots of cooked vegetables, tomatoes and citrus fruits were less likely to experience shortness of breath, wheezing and other severe symptoms of allergic rhinitis.
  3. Warm fluids like tea or soups may help to relieve nasal congestion and clear out the mucus.
  4. Take probiotics like yogurt as they have been proven to have anti-inflammatory effects that reduce the symptoms of allergic rhinitis.
  5. Consume food or beverages containing quercetin such as apples, onions and tea. Research has shown that quercetin is highly effective in fighting inflammation and providing allergy relief.
  6. Add magnesium-rich foods into your diet. Magnesium is an antihistamine, which helps provide allergy relief. Examples of food sources include almonds, cashew nuts, and wheat bran.

Supplement Recommendations:

  1. Keep your living and working environment clean to avoid relevant allergens (e.g. house dust mites, moulds, pet fur, pollens) and irritants (e.g. tobacco smoke) that trigger allergic rhinitis.
  2. Vacuum carpets in home or office on a regular basis as they usually contain a large number of mites, dust, and moulds.

Lifestyle Recommendations:

  1. Keep your living and working environment clean to avoid relevant allergens (e.g. house dust mites, moulds, pet fur, pollens) and irritants (e.g. tobacco smoke) that trigger allergic rhinitis.
  2. Vacuum carpets in home or office on a regular basis as they usually contain a large number of mites, dust, and moulds.

Result Explanation Recommendations:

  1. Incorporate 30-60 minutes of medium intensity exercises at least 3 to 5 times a week. Examples of exercises are cycling, swimming, and competitive sports.
  2. Incorporate resistance training such as weight lifting and bodyweight exercises at least 3 times a week.
  3. Consult a physical trainer to ensure safe training is maintained.
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