Health Risks Osteoporosis

Based on your genetics, your genetic predisposition for Osteoporosis is


What does this mean?

 Your genotypes indicate that you have a typical risk of osteoporosis.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is


This result is based on the SNPs(single nucleotide polymorphism)that are associated with Osteoporosis.

Your Genotype
What it means?
Genes: LRP5
Your Genotype: GG
What it means? Typical
Genes: ALDH7A1
Your Genotype: AA
What it means? Typical
Genes: VDR_intron8
Your Genotype: GG
What it means? Reduced risk
Genes: ESR1
Your Genotype: TT
What it means? Typical


This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Osteoporosis?

Osteoporosis is a bone disease that occurs when the body loses too much bone, makes too little bone, or both. As a result, bones become weak and may break from a fall or, in serious cases, from sneezing or minor bumps.

Osteoporosis is the most common bone disease in humans. It is a silent disease that affects an enormous number of people, of both sexes and all races, and it is more common in the ageing population. Osteoporosis is more commonly in Caucasians, women, and older people.

How It Affects Your Body

Bone tissue is continuously being resorbed and rebuilt; bone loss occurs if the resorption rate exceeds the formation rate. Bone resorption is a process of transferring calcium in the bone tissue to the blood by the breakdown of bone tissue.

With menopause and advancing age, an imbalance happens between resorption and formation rates of bone tissue where the resorption becomes higher than absorption, thereby reducing the bone density and strength. Fractures occurring spontaneously or following minor trauma such as fall from a standing height or less are more in severe osteoporotic individuals.


Risk Factors Can Influence The Risk of Developing Osteoporosis

Genetics are NOT the only risk factor for Osteoporosis.
Osteoporosis is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Osteoporosis.

Family History

If your parents or grandparents have had any signs of osteoporosis, such as a fractured hip after a minor fall, there is an increased likelihood of developing osteoporosis.


Women over the age of 50 are the most likely people to develop osteoporosis. The condition is 4 times as likely in women than men. Women's lighter, thinner bones and drastic decrease in estrogen are part of the reason they have a higher risk.


Your bone density peaks around age 30. After that, you’ll begin to lose bone mass.

Bone Structure and Body Weight

Petite and thin women have a greater chance of developing osteoporosis. One reason is that they have less bone mass to lose than women with more body weight and larger frames. Similarly, small-boned, thin men are at greater risk than men with larger frames and more bodyweight.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Have a balanced diet with plenty of fruits and vegetables, adequate dairy (calcium), and protein.
  2. Increase the intake of nuts and whole grains to increase the intake of minerals essential for bone health such as magnesium, copper, phosphorus, and more.
  3. Limit the intake of food with high refined sugar content such as soft drinks and fast food. It may impair calcium and magnesium uptake as well as accelerate calcium excretion.
  4. Make sure you have a sufficient intake of calcium. Good sources of calcium include low-fat dairy products, dark green leafy vegetables, canned salmon or sardines with bones, soy products (tofu), calcium-fortified cereals, and orange juice.

Lifestyle Recommendations:

  1. Stop smoking and reduce your alcohol intake, as it may prevent the lowering of your bone mineral density (BMD).
  2. Get at least 20 to 40 minutes of daylight exposure to support natural vitamin D production. Low sunlight exposure has been found to contribute to bone loss.
  3. Maintain a healthy body weight to reduce load stress on the bones.
  4. Consult a medical professional in the event of recurrent pains. Neck, wrist, and back pains are early signs of micro-fractures due to osteoporosis.

Exercise Recommendations:

  1. Incorporate load-bearing exercises such as resistance training regularly. Muscular stress on the bones stimulates bone repair which increases bone density and strength.
  2. Examples of load-bearing exercises include swimming, weightlifting, boxing, and competitive sports.
  3. Consult a physical trainer to ensure safe and adequate training intensity is applied.

Result Explanation Recommendations:

  1. Strengthening the muscles with weight training will support and protect your joints. If your joints are painful or swollen it is recommended you take a rest day or two in between workouts.
  2. Practice proper exercise techniques to avoid excessive joint stress. Consult a physical trainer to ensure proper form.
  3. Low-impact aerobic exercises are lighter and easier on your joints, for example walking, bicycling, swimming. Try not to strain your joints.
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