Health Risks Chronic Kidney Disease

Based on your genetics, your genetic predisposition for Chronic Kidney Disease is

Normal
Low
Normal
High

What does this mean?

 Your genotypes indicate that you have a typical risk for chronic kidney disease (CKD).

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

10.45

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Chronic Kidney Disease.

Genes
Your Genotype
What it means?
Genes: UMOD_exon7
Your Genotype: TT
What it means? Increased risk
Genes: UMOD_promoter
Your Genotype: GG
What it means? Increased risk
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Chronic Kidney Disease?

Chronic kidney disease (CKD) has been recognised as a worldwide public health problem, with outcomes of kidney failure, also known as end-stage renal disease (ESRD). Damage to your kidneys could result in the inability to filter your blood normally. The damage happens slowly, over a long period of time. When your blood is not filtered normally, the waste will build up in your body and cause other health illnesses such as cardiovascular disease and premature death. CKD is generally irreversible and usually fatal, unless renal replacement therapy (such as chronic dialysis or renal transplantation) is provided. The CKD progression to ESRD may be slowed down or halted with earlier diagnosis and effective management. The cause of CKD include hypertension (HTN), diabetes mellitus (DM), and inflammatory disorders.

Signs and Symptoms: Early Stages

Signs and Symptoms: Late Stages

Risk Factors Can Influence The Risk of Developing Chronic kidney disease

Genetics are NOT the only risk factor for Chronic Kidney Disease.
Chronic Kidney Disease is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Chronic Kidney Disease.

Risk Factors

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Maintain a healthy and balanced diet by fulfilling your daily nutritional requirements.
  2. Reduce salt intake by using minimal salt when cooking. You should also avoid consuming foods that have high salt content, such as salted fish, salted egg, anchovies, chips, etc.
  3. Eat plenty of fruits and vegetables daily for the absorption of a vast variety of minerals and vitamins.
  4. Consume moderate amounts of fish, meat, poultry, eggs, and legumes.
  5. Avoid consuming sugary beverages & sweet foods
  6. if possible, opt for low-sugar selections.
  7. Drink 6 - 8 glasses of water per day.
  8. Consume adequate amounts of dairy products.

Lifestyle Recommendations:

  1. Be sure to regularly get a full body medical checkup, as kidney function typically decreases with age.
  2. High blood pressure can lead to kidney damage. Discuss with your physician on how to control high blood pressure.
  3. Diabetic patients can have increased risk of kidney damage. Discuss with a physician to control glucose level.

Exercise Recommendations:

  1. Maintain a healthy BMI.
  2. Individuals aged 18 - 64 years old are recommended to have at least 150 minutes of moderate-intensity activities per week. For example, brisk walking, dancing, biking, gardening, etc. Otherwise, aerobic exercises of vigorous intensity can be done for 75 minutes per week. For example, fast swimming, running, climbing up a hill, basketball, etc.
  3. Individuals aged 65 years old and above can opt for exercises to improve flexibility, strength, and balance.

Result Explanation Recommendations:

  1. Avoid taking a nap in the middle of the day.
  2. Avoid unhealthy lifestyles and behaviours, including external eating (eating by external stimuli, such as the presence of food or its smell) and bedtime eating.
  3. Create a sleep conducive environment by sleeping in a quiet, dark and cool ambience
  4. you are recommended to use ear plugs or eye mask if necessary.
  5. Develop a pre-sleep routine by having relaxing activities and avoiding stress related work.
  6. Establish a consistent sleep schedule to have a set biological clock.
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