Nutrigenomics Vitamin D Requirement

Based on your genetics, your genetic predisposition for Vitamin D Requirement is

Normal
Low
Normal
High

What does this mean?

Likely to have no increased risk of vitamin D deficiency Your genotypes indicate that you are likely to have a typical serum level of vitamin D and no increased risk for vitamin D deficiency. Hence, maintain and monitor your vitamin D intake.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Vitamin D Requirement.

Genes
Your Genotype
What it means?
Genes: NADSYN1_intron2
Your Genotype: GT
What it means? Slightly higher risk for vitamin D insufficiency
Genes: GC_intron12
Your Genotype: AA
What it means? Typical
Genes: GC_exon11.1
Your Genotype: CC
What it means? Typical
Genes: GC_exon11.2
Your Genotype: TG
What it means? Lower serum 25(OH)D levels
Genes: GC_intron1
Your Genotype: TT
What it means? Typical
Genes: CYP2R1_promoter1.1
Your Genotype: AA
What it means? Higher 25(OH)D levels
Genes: CYP2R1_promoter1.2
Your Genotype: AA
What it means? Higher 25(OH)D levels
Genes: NADSYN1_intron
Your Genotype: AG
What it means? Lower serum levels of vitamin D
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Vitamin D Requirement?

Vitamin D is the sunshine vitamin. The human body can synthesise sufficient vitamin D when the skin is exposed to adequate amounts of sunlight. The dietary sources of vitamin D include food and dietary supplements. Vitamin D plays an essential role in the regulation of metabolism, calcium, and phosphorus absorption of bone health. Vitamin D adequacy is best determined by measurement of the 25-hydroxyvitamin D concentration (25(OH)D levels) in the blood.

How It Affects Your Body

Vitamin D aids in increasing calcium absorption in the intestines and maintaining bone growth and remodeling. Low vitamin D levels can cause soft bones (osteomalacia), deformed bones (rickets), and fragile, weak bones (osteoporosis). Low vitamin D levels can also affect the immune system and neurotransmitter productions, causing weakness, tiredness, nausea, and depression.

Symptoms

Old Age

Older individuals tend to have reduced sunlight exposure, dietary vitamin D intake, and produce less vitamin D under UV exposure.

Limited Sun Exposure

Limited UV is available to convert 7-dehydrocholesterol to pre-vitamin D3 in the skin.

Dark Skin

High melanin content in the skin reduces UV pnetration into the epidermis. Thus, less 7-dehydrocholesterol is converted to pre-vitamin D3.

Digestive Disorders

Vitamin D is fat-soluble and is absorbed in fat molecules in the intestines. Thus, reduced fat absorption reduces vitamin D absorption.

Obesity

Obese individuals have more subcutaneou fats that accumulate more vitamin D. This reduces the amount of available plasma vitamin D levels as well as increases dietary intake requirements.

Gastric bypass surgery

Individuals who have undergone gastric bypass surgery have less of the upper small intestines which absorb fats and vitamin D.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Consume adequate food rich in vitamin D daily.
  2. Natural sources of vitamin D include fatty fish, egg yolks, and cod liver oil.
  3. Common vitamin D fortified foods are cereals, bread, butter, milk, and yogurt.

Lifestyle Recommendations:

    Exercise Recommendations:

    1. Incorporate 30-60 minutes of medium intensity exercises at least 3 to 5 times a week to reduce body fat. Examples of exercises are cycling, swimming, and competitive sports.
    2. Incorporate resistance training such as weight lifting and bodyweight exercises at least 3 times a week to reduce body fat.

    Result Explanation Recommendations:

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      If you think you have the symptoms, consult with a healthcare professional.