Weight Management Low-Fat Diet Effectiveness

Based on your genetics, your genetic predisposition for Low-Fat Diet Effectiveness is


What does this mean?

 Your genotypes indicate that you are likely to have a typical weight loss response to low-fat diets. You may still choose low-fat diets if you would like to reduce weight, but it might not be as effective for you.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Low-Fat Diet Effectiveness.

Your Genotype
What it means?
Genes: PPARG_exon4
Your Genotype: CC
What it means? Typical
Genes: TFAP2B
Your Genotype: AA
What it means? Tendency to lose more weight on a low-fat diet than on a high-fat diet
Genes: APOA5/ZPR1
Your Genotype: CG
What it means? Amenable to benefit from a long term low-fat diet (reductions in total cholesterol and LDL cholesterol)
Your Genotype: CC
What it means? Typical
Genes: IRS1
Your Genotype: CC
What it means? Amenable to greater benefit (increased weight loss and insulin resistance improvement) on a high-carb
Genes: TCF7L2_intron3.2
Your Genotype: CC
What it means? No difference in the beneficial effects from weight-loss diets of varying fat content


This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Low-Fat Diet Effectiveness?

A low-fat diet is an energy-restricted diet in which the consumption of fats is generally less than 30% of total calories from fat. Very-low-fat diets consist of fat intake less than 10-15% of total calories from fat. Low-fat diet effectiveness is still debated by many. According to a study done by Tobias et al. (2015), low-fat diets are one of the most effective ways for long-term weight loss among adults. Other studies have also shown the effectiveness of low-fat diet when accompanied with high-protein or high-carbohydrate diet for a healthy weight loss and reduced fat mass. Having said that, the nutrient adequacy of low-fat diets is dependent on individual food selections.

How It Affects Your Body

A decrease in fat content in your diet will significantly reduce the level of cholesterol in the blood. This can be attributed to the low saturated fat content in the diet.

Although it is effective in reducing total cholesterol concentrations by 7-20%, it is good to note that the level of HDL-cholesterol (the good cholesterol associated with lower risk of heart disease) will also be reduced.

Low-fat diets can also help to fight heart diseases and diabetes. High-fat diets are associated with high calorie intake due to the foods that are energy-dense and very palatable. Therefore, low-fat diets often result in lower calorie intake, thus contributing to weight loss. However, cutting too much fats from the diet can also have health consequences like vitamin deficiency and depression.

Signs and Symptoms

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Beware of certain low-fat food as they are usually accompanied by a high carbohydrate intake, as many low-fat foods are based on sugar or highly-refined carbohydrates and often have energy values similar to their high-fat counterparts.
  2. Read the nutritional label of packaged food products when selecting your food.
  3. Choose healthier sources of fat, such as avocado, olive oil, nuts, seeds, unsaturated plant oils and fatty fish (eg. salmon, tuna and sardine).
  4. Limit the intake of margarine, mayonnaise, salad dressings, sauces and gravies as they are made with ingredients rich in fat.
  5. Eat lean meats and fish to help control your fat intake.

Lifestyle Recommendations:

  1. Consult a physician prior to switching to a low-fat high-protein diet.
  2. Steaming, stewing, boiling, poaching, baking instead of pan-frying or deep-frying.
  3. Opt to trim off visible fat from meats before cooking them.
  4. Reduce the amount of sauces and gravies in the dishes.

Result Explanation Recommendations:

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    If you think you have the symptoms, consult with a healthcare professional.