Health Risks Age-Related Macular Degeneration

Based on your genetics, your genetic predisposition for Age-Related Macular Degeneration is

High
19.56
0
6.59
100%

What does this mean?

 Your genotypes indicate that you have high risk for Age-Related Macular Degeneration.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

19.56

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Age-Related Macular Degeneration.

Genes
Your Genotype
What it means?
Genes: CFH_exon9
Your Genotype: TT
What it means? Typical
Genes: ARMS2/HTRA1
Your Genotype: TT
What it means? Greatly increased risk
Genes: CFH_exon2
Your Genotype: GG
What it means? Increased risk
Genes: TLR3
Your Genotype: CC
What it means? Typical
Genes: FRK/COL10A1
Your Genotype: CC
What it means? Typical
Genes: VEGFA
Your Genotype: TT
What it means? Increased risk for late-stage AMD
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Age-Related Macular Degeneration?

Age-related macular degeneration (AMD) arises when macula which is a spot near the center of the retina in the eyes becomes damaged. Macula is important for central vision which allows us to see object straight ahead. The center field view (central vision) will be disrupted and can appear blurry, distorted or even dark in those with AMD. People with AMD also lose their ability to see fine details regardless if the object is near or far.

AMD is a disease of the retina which accounts for 8.7% of blindness worldwide and is the leading cause of visual impairment in developed countries particularly in people older than 60 years. Its prevalence is likely to increase as a consequence of exponential population ageing.

How does age-related macular degeneration affect you?

AMD causes damage to the macula, the part of the eye needed for sharp, central vision, which lets us see objects that are straight ahead. This is necessary for recognising faces, reading books or using mobile phone screens, watching television, sewing, preparing food, driving, safely navigating stairs and performing other daily tasks we take for granted.

Symptoms of age-related macular degeneration

Risk Factors Can Influence The Risk of Developing Age-related macular degeneration

Genetics are NOT the only risk factor for Age-Related Macular Degeneration.
Age-Related Macular Degeneration is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Age-Related Macular Degeneration.

Ethnicity

People of European descent are more likely to develop AMD than people of African, Hispanic, and Asian descent.

Age

The risk of developing AMD increases greatly as a person ages. This condition is rarely diagnosed in people under the age of 50. Over the age of 80, 2-14% of people have AMD, depending on ethnicity.

Diet

Eating a healthy diet has been associated with a reduced risk of developing AMD. A healthy dietthat benefits the eyes emphasizes the consumption of dark green leafy vegetables, citrus fruits, nuts, and whole grains. Consuming healthy fats — found in fish, nuts, and olive oil — and minimizing saturated and trans fats are also important.

Family history

Parents, siblings, and children of an individual with AMD have a higher chance of developing AMD themselves.

Smoking

Smoking is associated with higher risk of developing AMD. If you smoke, quitting is one of the easiest ways to reduce your risk.

Suggested Lifestyle Changes

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