Health Risks Glaucoma

Based on your genetics, your genetic predisposition for Glaucoma is

Normal
Low
Normal
High

What does this mean?

 Your genotypes indicate that you have a typical risk of glaucoma. Maintain a healthy diet and lifestyle to avoid glaucoma.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

1.88

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Glaucoma.

Genes
Your Genotype
What it means?
Genes: LOXL1
Your Genotype: GG
What it means? Higher exfoliation glaucoma risk
Genes: CDKN2B-AS1
Your Genotype: AG
What it means? Lower risk for developing glaucoma
Genes: TGFBR3/CDC7
Your Genotype: AA
What it means? Typical
Genes: CAV1/CAV2
Your Genotype: GG
What it means? Typical
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Glaucoma?

Glaucoma is a disease that causes vision loss, typically begins with damage in the optic nerve, and eventually causes total blindness of the eye. The optic nerve responsible for transmitting information from the eye to the brain and the other way around. Glaucoma is caused by multiple factors that result in the morphological changes of the retina. Open-angle and angle-closure, marked by an increase in eye pressure, are the two main types of glaucoma. Apart from acute angle-closure glaucoma, all other forms of chronic glaucoma are largely showing no symptoms, with the only signs of gradually progressive visual field loss and optic nerve changes. Glaucoma can also happen with damage occurring to the optic nerve without eye pressure exceeding the normal range around 12-22 mm Hg. Glaucoma disproportionately affects women and Asians. Other high-risk groups including people over 60 years old, family members of those already diagnosed, steroid users, diabetics, high myopia, hypertension, central corneal thickness <5mm, and eye injury.

How It Affects Your Sight

Glaucoma is usually caused by the increase in eye pressure, which in turn damages the eye nerve. Apart from acute angle-closure glaucoma, all other forms of chronic glaucoma mostly show no symptoms, with the only signs being the gradual progressive loss of visual field and optic nerve changes.

How does Glaucoma affect your sight?

Glaucoma usually results from the increase of the eye pressure which in turn damages the eye nerve.

Symptoms

Risk Factors Can Influence The Risk of Developing Glaucoma

Genetics are NOT the only risk factor for Glaucoma.
Glaucoma is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Glaucoma.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Consume more foods that contain carotenoid as they are good for sight health. Examples of vegetables and fruits rich in carotenoids: carrots, yams, sweet potatoes, papaya, watermelon, cantaloupe, mangoes, tomatoes, bell peppers and oranges.
  2. Consume more foods that contain vitamin A & C. For example, collard greens, cabbage, kale, spinach, Brussels sprouts, celery, carrots, peaches, radishes, green beans, and beets.
  3. Do not drink more than 5 cups of coffee in a day. Minimize coffee intake as it modifies the gene that is responsible for high risk of glaucoma.
  4. It is advised to consume more leafy green vegetables as a diet that is high in nitrate was found to be associated with a lower risk of open-angle glaucoma.
  5. Dietary intake of calcium and iron were found to be associated with decreased risk for glaucoma but consumption of mineral supplements with iron, calcium and magnesium might increase the risk of glaucoma.

Supplement Recommendations:

  1. To prevent glaucoma, it is recommended to take multivitamin pills that contain vitamin A, B-complex, E, C, zinc, magnesium, and calcium.
  2. Omega-3 oil is important for general eye health.
  3. Dietary intake of calcium and iron were found to be associated with decreased risk for glaucoma but consumption of mineral supplements with iron, calcium and magnesium might increase the risk of glaucoma.
  4. High intake of retinol equivalents and vitamin B1 has shown to have a protective effect on open-angle glaucoma.

Lifestyle Recommendations:

  1. Consume sufficient water throughout the day.
  2. Be sure to always maintain a normal blood pressure.
  3. It is advised that you should not smoke, or stop smoking if you are a smoker.
  4. If you have known family history of glaucoma, be sure to regularly get dilated eye examinations every 5 - 10 years. The risk of glaucoma will increase with age, hence more frequent visits are required as you age as well.
  5. Diabetic patients are at higher risks of getting glaucoma. Be sure to control your blood sugar level as recommended by your doctor.
  6. Certain drugs may cause glaucoma
  7. be sure to check with your doctor.

Exercise Recommendations:

  1. Studies have found that regular aerobic exercise can decrease intraocular pressure.
  2. Aerobic exercises are highly recommended for a duration of 45 minutes, 3 - 4 times a week
  3. such as brisk walking, swimming, cycling and jogging.
  4. Certain activities like weightlifting, sprinting, and yoga (in certain positions) may also increase eye pressure. It is advised that you should practice those with caution or under the advice of your doctor.
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