Health Risks Obesity

Based on your genetics, your genetic predisposition for Obesity is

Normal
Low
Normal
High

What does this mean?

Likely to have typical risk of obesity Your genotypes are associated with typical risks for obesity. See recommendations below on how to lose weight or avoid becoming overweight or obese.

How Is Your Genetic Risk Calculated?

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Obesity.

Genes
Your Genotype
What it means?
Genes: FTO_intron1.1
Your Genotype: TT
What it means? Typical
Genes: MC4R
Your Genotype: TT
What it means? Typical
Genes: SDC3
Your Genotype: CT
What it means? Typical
Genes: PPARG_exon4
Your Genotype: CC
What it means? Typical
Genes: IL6
Your Genotype: GG
What it means? Typical
Genes: TMEM18
Your Genotype: GG
What it means? Risk of increased weight
Genes: SFRS10-ETV5-DGKG
Your Genotype: CC
What it means? Increase risk of obesity
Genes: BDNF_intron
Your Genotype: GG
What it means? Typical
Genes: APOA2
Your Genotype: TT
What it means? Lower obesity risk
Genes: APOA5_promoter
Your Genotype: TC
What it means? Lower obesity risk
Genes: FTO_intron1.3
Your Genotype: CT
What it means? Increased risk for Early Onset Extreme Obesity
Genes: ADIPOQ_promoter2
Your Genotype: CG
What it means? Higher risk of obesity
Genes: FAM71F1
Your Genotype: AG
What it means? Increased risk of obesity
Genes: PCDH15
Your Genotype: AA
What it means? Typical
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Obesity?

A person’s body weight is determined by the sum of energy intake and energy expenditure. An imbalance between total energy intake and expenditure will results in body weight changes. One of the outcomes of this imbalance is obesity, a major global health problem, with 500 million obese individuals worldwide.

Many studies have highlighted the role of genetic factors in obesity. Usually, these genes code for proteins involved in the regulation of satiety and food intake. Some of the other factors contribute to the obesity in children includes the deficiency in the leptin hormone which causes an early-onset extreme obesity.

How It Affects Your Body

Obesity affects the body in many ways. Increased weight and relative fat causes increased inflammatory syndromes, vascular damage and blockage, hormonal dysfunctions, energy balance disturbances, musculoskeletal damage, affects mental health, and more.

It predisposes individuals to several comorbidities, including hypertension, dyslipidemia, coronary heart disease, type 2 diabetes, stroke, cancer and osteoarthritis, and a shortened life expectancy while impairing the quality of life. Therefore, managing the ideal body weight is an important part of staying healthy.

Symptoms

Risk Factors Can Influence The Risk of Developing Obesity

Genetics are NOT the only risk factor for Obesity.
Obesity is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Obesity.

Diet

Diet high in refined sugar, calorie-rich food, saturated fats, and LDL cholesterols increases the risk of obesity. High carbohydrate intake instead of fats and proteins have been associated with weight gain.

Physical Activity

Physical inactivity is a major cause of weight gain and obesity. This is due to reduced calorie expenditure and increased fat deposition.

Sleep

Poor sleep quality and quantity increase weight gain contributing to obesity. This is due to poor hormonal balance leading to increased hunger and fat deposition.

Family History

If you have a parent, sibling, or cousin who is overweight or obese, you have an increased risk of obesity.

Depression

Depression has been shown in alter behavior towards promoting unhealthy eating and lifestyle habits which can lead to gaining weight.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Reduce refined sugar and high glycemic index carbohydrates such as white rice, noodles, and pastries.
  2. Eat plenty of vegetables, fruits, and whole-grain products to achieve and maintain weight.
  3. Choose lean meats, poultry, fish, lentils, and beans for protein. Avoid processed meat and fried foods rich in saturated fats and LDL.
  4. Drink plenty of water. Substitute sweet beverages with green tea which has the potential to promote weight loss.
  5. Substitute sugar with low-calorie sweeteners in your beverages.
  6. Consume at least 3 servings of yogurt a day. Yogurt consumption is found to be associated with lowering body mass index, lowering body weight, and smaller waist circumference.
  7. Eggs are high in protein and healthy fats. Consume eggs with low glycemic index carbohydrates such as oats and bananas during breakfast enhances weight loss.

Lifestyle Recommendations:

  1. Improve the quality and quantity of sleep. Aim to achieve 6-8 hours of uninterrupted sleep. Lack of quality sleep disturbs systemic functions leading to increased calorie intake and reduced energy expenditure.
  2. Opt to cook meals instead of eating out. Meal quality and quantity can be better preserved by choosing ingredients.

Exercise Recommendations:

  1. Incorporate 30-60 minutes of medium intensity exercises at least 3 to 5 times a week. Examples of exercises are cycling, running, and competitive sports.
  2. Incorporate resistance training such as weight lifting and bodyweight exercises at least 3 times a week.
  3. Follow-up weight-training sessions with 30 minutes of cardio exercises such as cycling to improve fat-loss.
  4. Incorporate intense 30-60 minutes of swimming at least 4 times a week. Swimming has been shown to be the most efficient in burning calories and improving body composition.
  5. Consult a physical trainer to ensure adequate training technique and intensity is followed.

Result Explanation Recommendations:

  1. Incorporate 30-60 minutes of moderate-intensity exercise at least 5 times a week. Brisk walks, jogging, and cycling are great aerobic exercises.
  2. Incorporate resistance training at least 3 times a week. This includes swimming, weightlifting, and boxing.
  3. Aim to improve body composition with the goal of increasing muscle mass and reducing body fat percentage.
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