Health Risks Osteoarthritis

Based on your genetics, your genetic predisposition for Osteoarthritis is


What does this mean?

 Your genotypes indicate that you have low risk for Osteoarthritis.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is


This result is based on the SNPs(single nucleotide polymorphism)that are associated with Osteoarthritis.

Your Genotype
What it means?
Genes: IL1B
Your Genotype: CC
What it means? Typical
Genes: COL6A4P1
Your Genotype: GG
What it means? Typical


This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Osteoarthritis?

Osteoarthritis is the most common type of arthritis (informally known as joint disease), which occurs when the cartilage (a cushioning surface or rubber like padding) that protects the ends of the bones at the joints, wears down over the time. This will cause the bone to rub against another bone, leading to pain, swelling and stiffness to the joint.

In healthy cartilage, there is a balance between buildup and breakdown of the tissue. This balance is lost in osteoarthritis, leading to cartilage damage and, over time, complete breakdown. Without the protection of the cartilage, bone damage occurs at the joint. In response, the body builds new bone, which leads to overgrowth and reduced mobility of the joints. In addition, the cartilage damage triggers an immune response, causing inflammation of other joint tissues and leading to further joint damage.

How does osteoarthritis affect you?

Osteoarthritis can occur in any joint, but it often affected joints in the hands, knees, hips, and spine. In the long run the joints can become weak and the pain may become worse. This disorder is often asymmetric where a patient may have severe, debilitating osteoarthritis of one knee with almost normal function of the opposite leg.

A day to day activity becomes challenging to perform due to the pain and stiffness caused by OA.

Symptoms of Osteoarthritis

Risk Factors Can Influence The Risk of Developing Osteoarthritis

Genetics are NOT the only risk factor for Osteoarthritis.
Osteoarthritis is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Osteoarthritis.


Significant injury, such as ligament damage, can eventually lead to osteoarthritis.


Women are more likely to develop osteoarthritis, compared to men.


Excessive weight can put stress on joints and promote cartilage damage.


Osteoarthritis is more common among the elderly, but even young adults can develop osteoarthritis.

Suggested Lifestyle Changes

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