Health Risks Parkinson's Disease

Based on your genetics, your genetic predisposition for Parkinson's Disease is

Normal
Low
Normal
High

What does this mean?

 Your genotypes indicate that you have a typical risk for Parkinson's disease.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

0.21

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Parkinson's Disease.

Genes
Your Genotype
What it means?
Genes: SNCA_intron4
Your Genotype: CT
What it means? Slightly increased risk of Parkinson's disease
Genes: SNCA_3'-region
Your Genotype: --
What it means? --
Genes: MCCC1
Your Genotype: GG
What it means? Reduced risk
Genes: LRRK2
Your Genotype: GG
What it means? Typical
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Parkinson's Disease?

Parkinson's disease is characterised by tremor, slowed movement, rigidity, and postural instability. It is the second most common neurodegenerative disorder after Alzheimer's disease. A neurodegenerative disorder is a condition whereby brain cells are either dysfunctioning or dying, resulting in loss of communication between cells. Parkinson’s disease affects more than 1% of 55-year-old individuals and more than 3% of those over 75 years of age. The age of disease onset is widely variable, ranging from juvenile to very late in life with an average age of onset of 60 years. Generally, individuals with onset before age 20 are considered to have juvenile-onset; those with onset between 20 and 50 years of age are classified as having early-onset; and those with onset after age 50 are referred to as late-onset. There is a higher prevalence among men than among women.

How It Affects Your Brain

Parkinson?s disease gradually changes the brain's mental functions, which include the ability to memorise and to pay attention. The effect of Parkinson?s disease on the brain starts in a region of the brain that plays a vital role in movement. The symptoms result in the inability to initiate movement and display facial expressions.

How does it affect your brain?

Parkinson’s disease gradually changes the brain's mental functions which include the ability to memorise and to pay attention. The effect of Parkinson’s disease on the brain starts in a region of the brain that plays a vital role in movement. The symptoms result in the inability to initiate movement and display facial expressions.

Symptoms

Risk Factors Can Influence The Risk of Developing Parkinson's disease

Genetics are NOT the only risk factor for Parkinson's Disease.
Parkinson's Disease is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Parkinson's Disease.

Head Trauma

Head injury are often related to increased risk of Parkinson’s disease.

Environtmental

Long term exposure to certain chemicals like pesticides can lead to cellular mutation that is associated with an increased risk of Parkinson’s disease.

Gender

Male are more likely to develop Parkinson’s disease than female.

Age

The common onset of Parkinson’s disease is the age above 60 years old.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Maintain a healthy and well-balanced diet for the welfare of mental health and physical health, which can reduce the risk of Parkinson? disease.
  2. Eating a variety of vegetables and fruits is essential to obtain vitamins and minerals needed for bodily functions.
  3. Nuts (e.g. walnuts) are rich in omega-3, which are excellent for the maintenance of brain health.
  4. Moderate consumption of coffee and tea can reduce the risk of developing parkinson? disease.
  5. Include vitamin E-rich foods in your diet. Individuals with high dietary vitamin E intake have reduced risk of Parkinson's disease.

Lifestyle Recommendations:

  1. Maintain good sleep hygiene for good mental health.

Exercise Recommendations:

  1. Physical exercise has been associated with lower risk of developing Parkinson's disease.
  2. Regularly exercising from a younger age can help to lower the risk to develop Parkinson? disease in an individual? later years.
  3. Establish a regular exercise routine of at least 75 minutes per week to promote flexibility, strength, mobility and balance.
  4. Physical exercises, such as walking training, t'ai chi and tango dancing, have been reported to improve disease symptoms, mobility, balance, gait and quality of life.
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