Health Risks Hypertriglyceridaemia

Based on your genetics, your genetic predisposition for Hypertriglyceridaemia is

Normal
10.23
0
42.23
100%

What does this mean?

 Your genotypes indicate that you have normal risk for Hypertriglyceridaemia.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is

10.23

This result is based on the SNPs(single nucleotide polymorphism)that are associated with Hypertriglyceridaemia.

Genes
Your Genotype
What it means?
Genes: GCKR_exon15
Your Genotype: CT
What it means? Increased risk
Genes: APOA5_promoter
Your Genotype: CT
What it means? Increased risk of severe hypertriglyceridaemia
Genes: ZPR1
Your Genotype: CG
What it means? Increased risk
Genes: APOA5_exon2
Your Genotype: CC
What it means? Typical
Genes: GALNT2
Your Genotype: AG
What it means? Increased risk of severe hypertriglyceridaemia
Genes: TBL2
Your Genotype: CT
What it means? Increased risk of severe hypertriglyceridaemia
Genes: ANGPTL3
Your Genotype: CC
What it means? Increased risk of severe hypertriglyceridaemia
Genes: GCKR_intron16
Your Genotype: CT
What it means? Increased risk of severe hypertriglyceridaemia
Genes: LPL_exon9
Your Genotype: CC
What it means? Typical
Genes: LPL_3'downstream
Your Genotype: GG
What it means? Typical
Genes: LPL_intergenic
Your Genotype: AA
What it means? Increased risk
Genes: TRIB1
Your Genotype: TT
What it means? Typical
Genes: DOCK7_intron7
Your Genotype: TT
What it means? Increased risk
Genes: AFF1
Your Genotype: GT
What it means? Increased risk
Genes: CYP26A1
Your Genotype: AA
What it means? Typical
Genes: SUGP1
Your Genotype: TT
What it means? Increased risk
Genes: APOB_exon30
Your Genotype: CT
What it means? Increased risk
Genes: DOCK7_intron5b
Your Genotype: AA
What it means? Typical
Genes: CILP2_PBX4_intergenic
Your Genotype: CC
What it means? Typical
Genes: FADS
Your Genotype: CT
What it means? Increased risk
Genes: XKR6
Your Genotype: GG
What it means? Reduced risk
Genes: PCIF1
Your Genotype: TT
What it means? Typical
!

Limitations

This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Hypertriglyceridaemia?

Triglycerides are a type of fat found in the blood. When you eat, your body converts any calories it doesn't need to use right away into triglycerides. They are stored in your fat cells. Later, hormones release triglycerides for energy in between meals.

However having high triglyceridemia levels (hypertriglyceridemia) means you have too much of this type of fat in your blood, which is not good. Too much fat in the blood can contribute to thickening of the blood vessels of the heart (arteries), which increases the chances of developing stroke, heart attack and heart disease and in extreme cases can cause inflammation to the pancreas.

Mild and moderate hypertriglyceridemia have the triglycerides measurement of 150–999 mg/dL. Severe and very severe hypertriglyceridemia triglycerides have the measurement of > 1000 mg/dL.

Certain genetic variations play a role in triglyceride metabolism (how the body process and converts fat to energy), which can lead to slower triglyceride metabolism. Secondary causes are due to lifestyle and environmental factors, such as, high fat diet, obesity, diabetes, hypothyroidism, and certain medications.

How does high triglyceride levels affect the body?

In both men and women, increasing levels of non-fasting triglyceride significantly increases the risk of heart related complications. For example: heart attack, heart disease, thickening of the walls in the arteries and inflammation of the pancreas.

Symptoms of hypertriglyceridemia

Risk Factors Can Influence The Risk of Developing Hypertriglyceridaemia

Genetics are NOT the only risk factor for Hypertriglyceridaemia.
Hypertriglyceridaemia is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Hypertriglyceridaemia.

Lack of Exercise

Having a lack of exercise or leading a sedentary lifestyle increases the risk of developing high triglyceride levels.

Smoking

Smoking tobacco increases the risk of developing high triglyceride levels.

Weight

Being overweight or obese increases the risk of developing high triglyceride levels.

Blood Pressure

Having high blood pressure increases the risk of developing high triglyceride levels.

Diabetes

Having high blood sugar and diabetes increases the risk of developing high triglyceride levels.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Aim to avoid or limit your alcohol intake, as alcohol consumption is one of the risk factors of high triglyceride levels.
  2. Avoid food with simple carbohydrates like fructose, as these increase triglyceride levels.
  3. Having a low fat diet (fat content is <30% of total daily caloric intake) could help in reducing triglyceride levels.
  4. If your triglyceride levels is more than 1000 mg/dL, a very low fat diet (<15% of daily caloric intake from fat) is strongly recommended.

Exercise Recommendations:

  1. Start with 20-30 minutes of aerobic activity -- anything that gets your heart rate up. Do that for 5 days a week, and your overall cholesterol levels may drop while your good cholesterol will rise.
  2. Examples of aerobic activities are basketball, cycling, jumping rope, kickboxing, football.
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