Health Risks Hypertension

Based on your genetics, your genetic predisposition for Hypertension is


What does this mean?

 Your genotypes indicate that you have a typical risk for hypertension. See below for some recommendations to maintain a healthy diet and lifestyle.

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is


This result is based on the SNPs(single nucleotide polymorphism)that are associated with Hypertension.

Your Genotype
What it means?
Genes: AGTR1
Your Genotype: AA
What it means? Typical
Genes: STK39
Your Genotype: GG
What it means? Typical


This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Hypertension?

Hypertension, or high blood pressure, refers to the force of the body’s blood pushing against the inner walls of the blood vessels, especially the arteries (blood vessels in the heart). Each time the heart contracts, it pumps blood into the arteries.

Blood pressure is not constant throughout the day, it is lowest when you’re sleeping and it can also go up when you are excited, nervous or physically active.

A healthy blood pressure is below 120/80 mmHg (millimetres of mercury), expressed verbally as 120 over 80. A blood pressure of 140/90 mmHg or higher indicates high blood pressure in subjects who are not taking antihypertensive medication or better known as medication for high blood pressure.

Blood pressure is measured both by the amount of blood the heart pumps and the amount of resistance for blood flow in your arteries. When the arteries are tighten or becomes constricted, the heart has to put in more effort to pump blood into the small spaces of the artery, an this creates pressure inside the artery.

How does high blood pressure affect you?

1. Stroke
Cerebral hemorrhage is due to the artery in the brain bursting and causing a blood clot in the brain which stops the flow of blood. Blood clot is a clump of blood which has become semi-solid.
Cerebral infarction known as stroke, happens when the brain cells die due insufficient blood supply forming something like an wound.

2. Coronary heart disease
The accumulation of plaque (fat,cholesterol) in the blood vessels of heart (artery) is known as arteriosclerosis. High blood pressure adds extra force to the blood vessels of the heart. In a long run high blood pressure can damage the arteries, making them more susceptible to the narrowing and plaque accumulation related to atherosclerosis. Narrowed artery limits or blocks the blood flow to the heart muscle. This prevents the heart from getting enough oxygen supply. When this progressfurther, patients can get chest pain when they exert themselves. The hardened artery due fat deposits will likely be prone to have small blood clots than can cause heart attack or stroke.

3. Kidney damage
Lack of blood supply to the kidney can also damage the kidney

4. Eye damage
High blood pressure can cause the tiny blood vessels of the eye to bleed if you have diabetes. A condition known as retinopathy which can cause blindness.

How It Affects Your Body

Hypertension causes damage to blood vessels over time. Depending on the severity of vessels, different complications may arise in different parts of our body. Vessels damage in the brain may lead to aneurysms, dementia, cognitive, stroke, and motor function deterioration. Vision and other sensory functions may also be affected. Heart complications may arise due to cardiac stress, leading to cardiovascular complications such as heart arrhythmia and failure. Renal and other organ functions may also deteriorate. Sexual performance and ability may also drastically deteriorate due to the inability to supply and maintain sufficient blood to the sexual organs.

What are the symptoms of hypertension?


Risk Factors Can Influence The Risk of Developing Hypertension

Genetics are NOT the only risk factor for Hypertension.
Hypertension is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Hypertension.


As we age, our blood vessels gradually lose some of their elastic quality, which can contribute to increased blood pressure.


Until age 64, men are more likely to get high blood pressure than women are. At 65 and older, women are more likely to get high blood pressure.


Being overweight or obese, and the lack of physical activities increases the risk of developing high blood pressure.


A diet that is too high in salt consumption, as well as calories, saturated and trans fat, and sugar, carries an additional risk of high blood pressure.


Using tobacco can cause your blood pressure to temporarily increase and can contribute to damaged arteries. Secondhand smoke, exposure to other people’s smoke, also increases the risk of heart disease for nonsmokers.

Family History

If your parents or other close blood relatives have high blood pressure, there’s an increased chance of developing high blood pressure.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Aim to have a healthier diet regime including eating more fruits, vegetables, and fish, and reducing saturated fat intake.
  2. Aim to reduce your salt intake by avoiding processed (fried food, canned food, fast food) foods that commonly contain high salt (sodium) content.
  3. Reduce alcohol consumption. Excessive alcohol consumption can damage the blood vessels which increases the risk of hypertension.

Lifestyle Recommendations:

  1. Avoid or quit smoking as smoking is one of the major risk factors for high blood pressure.
  2. Maintain a healthy weight. Being overweight or obese drastically increase the risk of hypertension.
  3. Aim to increase your physical activity. Have modest levels of aerobic exercise on a regular basis (e.g. brisk walk or swim for 30-45 min, 3-4 times a week).

Result Explanation Recommendations:

  1. Folate intake and coffee consumption can reduce the risk of gout.
  2. Avoid high consumption of meat, seafood, food high in fructose (sugar), and sweetened soft drinks as they can increase the risk of gout.
  3. Avoid or reduce consumption of food with high levels of purines. Some examples of high purine food are meat (liver and kidney) and seafood (anchovies and sardine).
  4. Consumption of vegetables and low-fat / non-fat dairy products may help to reduce the frequency of flare-ups in gout.
  5. Reducing alcohol consumption can help reduce the risk of developing gout.
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