Health Risks Chronic Kidney Disease

Based on your genetics, your genetic predisposition for Chronic Kidney Disease is


What does this mean?

 Your genotypes indicate that you have a typical risk for chronic kidney disease (CKD).

How Is Your Genetic Risk Calculated?

Your genetic risk assessment is


This result is based on the SNPs(single nucleotide polymorphism)that are associated with Chronic Kidney Disease.

Your Genotype
What it means?
Genes: UMOD_promoter
Your Genotype: GG
What it means? Increased risk
Genes: UMOD_exon7
Your Genotype: TT
What it means? Increased risk


This report does not diagnose any health conditions or provide medical advice. This should not be used as a diagnostic tool.
This result is limited to existing scientific research.
Please consult with a healthcare professional before making any major lifestyle changes or if you have any other concerns about your results.

What is Chronic Kidney Disease?

Chronic kidney disease (CKD) has been recognised as a worldwide public health problem, with outcomes of kidney failure, also known as end-stage renal disease (ESRD). Damage to your kidneys could result in the inability to filter your blood normally. The damage happens slowly, over a long period of time. When your blood is not filtered normally, the waste will build up in your body and cause other health illnesses such as cardiovascular disease and premature death. CKD is generally irreversible and usually fatal, unless renal replacement therapy (such as chronic dialysis or renal transplantation) is provided. The CKD progression to ESRD may be slowed down or halted with earlier diagnosis and effective management. The cause of CKD include hypertension (HTN), diabetes mellitus (DM), and inflammatory disorders.

Signs and Symptoms: Late Stages

Signs and Symptoms: Early Stages

Symptoms of CKD? ( Large Stage )

Symptoms of CKD? ( Early Stage )

Risk Factors Can Influence The Risk of Developing Chronic kidney disease

Genetics are NOT the only risk factor for Chronic Kidney Disease.
Chronic Kidney Disease is believed to be caused by a combination of environmental, genetic and lifestyle factors. Now that you have learnt about your genetic risk, you can determine how aggressively you need to make lifestyle changes to reduce your risk.
The earlier in your life that you commit to living a healthy lifestyle, the more you can reduce your risk for or delay the development of Chronic Kidney Disease.

Risk Factors


Certain drugs tend to damage the kidney or are insufficiently eliminated due to poorly functioning kidneys, resulting in accumulation of the drugs in the body. Some drugs may also cause toxic side effects.


Individuals that are blood-related to a person with high blood pressure, diabetes or chronic kidney disease, are more likely to develop the disease as well.


Research has shown that diabetes, heart diseases, and high blood pressure are associated with higher risk for chronic kidney disease.


The risk of developing chronic kidney disease significantly increases with age. This condition is most often diagnosed in individuals above the age of 65.

Suggested Lifestyle Changes

Dietary Recommendations:

  1. Maintain a healthy and balanced diet by fulfilling your daily nutritional requirements.
  2. Reduce salt intake by using minimal salt when cooking. You should also avoid consuming foods that have high salt content, such as salted fish, salted egg, anchovies, chips, etc.
  3. Eat plenty of fruits and vegetables daily for the absorption of a vast variety of minerals and vitamins.
  4. Consume moderate amounts of fish, meat, poultry, eggs, and legumes.
  5. Avoid consuming sugary beverages & sweet foods
  6. if possible, opt for low-sugar selections.
  7. Drink 6 - 8 glasses of water per day.
  8. Consume adequate amounts of dairy products.

Lifestyle Recommendations:

  1. Be sure to regularly get a full body medical checkup, as kidney function typically decreases with age.
  2. High blood pressure can lead to kidney damage. Discuss with your physician on how to control high blood pressure.
  3. Diabetic patients can have increased risk of kidney damage. Discuss with a physician to control glucose level.

Lifestyle Recommendations:

  1. Consistent full body medical checkup. As age increases, kidney function decreases gradually.
  2. High blood pressure can lead to kidney damage discuss with your doctor on how to control high blood pressure
  3. Diabetic patients can have increase risk of kidney damage, discuss with physician to control glucose level

Exercise Recommendations:

  1. Maintain a healthy BMI.
  2. Individuals aged 18 - 64 years old are recommended to have at least 150 minutes of moderate-intensity activities per week. For example, brisk walking, dancing, biking, gardening, etc. Otherwise, aerobic exercises of vigorous intensity can be done for 75 minutes per week. For example, fast swimming, running, climbing up a hill, basketball, etc.
  3. Individuals aged 65 years old and above can opt for exercises to improve flexibility, strength, and balance.
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